Skip to main content

What is MixedDNA

MixedDNA is a general-purpose Computer-Aid Design (CAD) and modeling tool for genetic engineering. It is a desktop application for Mac, Windows and Linux.

MixedDNA is more than a sequence editor and has been built to empower genetic engineering as a tool that everyone can use, not just experts.

Secrets to Success in Genetic Engineering​

If you’ve ever tried to transform an organism, you know it can go off the rails quickly, leaving you with empty agar plates and a lot of disappointment. Mixed believes that there are a few secrets to success in synthetic biology that are perhaps not well understood:

  • Build libraries, not single constructs
  • Use standardized and well-characterized parts
  • Understand that in-silico validation and modeling can’t do everything, but it can save you from yourself

Build Libraries, Not Single Constructs​

Biology is complicated, and inevitably there are parts of your experimental system that are not fully understood. By trying several variants of your design or sequences, you can avoid failures and better explore the solution space. Factors such as codon selection of your proteins, promoter and terminator strength, and the genetic loci that you integrate into all affect your success. Mixed helps you optimize these factors and many more.